CASI

CAS lnnovations (CASI) is a venture builder and independent investment company that works in deep partnership with CETAV as well as CAS to turn world-class academic research into high-impact commercial companies. CASI identifies projects, resolves key IP and commercialisation barriers, and prepares technologies for spinout via a structured incubation and investment program. Each year, CASI develops a focused cohort of up to 1O investable spinouts across optics and semiconductors, advanced materials, biotechnology, quantum technologies, energy, Al and data-driven solutions.

CASIP

The Venture lncubation Program by CAS lnnovations (CASIP) is a structured 12-month platform designed to transform breakthrough research from the Czech Academy of Sciences into investment-ready spinouts. Each year, the Program selects around 1O high-potential projects from an active pipeline and provides them with targeted support across team formation, IP strategy, product development, MVP and PMF validation, regulatory and go-to-market planning, and investor readiness. With dedicated capital, hands-on venture-building, and access to industry, academic, and VC networks, the program systematically prepares each project to launch as a credible spinout.

The CASIP Advantage

CASIP brings a unique combination of world-class science, structured venture-building, and experienced execution to transform high-potential research into successful deep-tech companies. Leveraging the Czech Academy of Sciences' scale CASI (investment manager of CASIP) applies a rigorous selection and incubation framework that removes barriers to technology transfer and equips scientists with the founding team, IP, product strategy, and market validation needed for growth. With professional governance, strong industry and VC networks, and aligned incentives, CASIP will create lasting value for lead scientists, the Academy, and investors by building globally competitive spinouts from exceptional Czech research.

Unique Partnership

  • Strategie relationship with CAS
  • Access to 52 research institutes & 7,500+ scientists
  • Active cooperation with CETAV

Target Sectors

The program targets deep-tech sectors where CAS holds scientific advantage and where technologies have strong pathways to scalable commercialisation and global market impact.

World-Class Science

  • Unrivalled access to CAS scientific IP
  • 10th globally among funded R&D orgs. in 2024
  • Breakthroughs in deep tech and life sciences fields

Deep Tech

  • AI/Semiconductors
  • Optics
  • Energy

Proven Model

  • Structured and highly-focused venture incubation
  • Translating science into high-value companies
  • Systematically creating 8-10 new ventures a year

Life Sciences

  • Therapeutics
  • Enabling Platforms
  • Precision Medicine

Strong Network

  • Deep tech VCs, CVCs, and private investors
  • Global research-institution partnerships
  • Other deep tech incubators and accelerators

HealthTech

  • Diagnostics & Devices
  • Data & Discovery
  • Care Delivery
Program Terms
Venture Program An annual deep-tech incubation program of the Czech Academy of Sciences
Management CAS lnnovations a.s. ("CASI")
A program manager responsible for deal sourcing, incubation execution, and portfolio management
Sector Focus Deep Tech: Al & Semiconductors, Optics, Energy
Life Sciences: Therapeutics, Enabling Platforms, Precision Medicine 
HealthTech: Diagnostics & Devices, Data & Discovery, Care Delivery 
Project Sourcing Projects to be sources by CASI in cooperation with CETAV
CASI draws on 52 institutes (~ 7,500 scientists) under CAS and 120+ commercialisation projects within CETAV 
Project Selection Projects are selected using a structured evaluation framework
Cohort Size ~ 10 projects selected for incubation annually
Program Duration A standardised 12-month incubation program
lnitial lnvestment Each project receives approximately 125,000 EUR (3 million CZK) during incubation
Follow-on lnvestment Capital allocated for follow-on investments in top-performing spinouts
Deliverables Each project shall graduate with a founding team, validated customer and market insights, a defined MVP, a robust business model and pian, investor-ready materials, and an incorporated spinout ready for pre-seed/seed

 

Team
MS

Martin Smekal
CEO
Head of CETAV
25 Years of Experience

IN Ivan Nechvátal
COO
16 Years Experience
OH Ondřej Hložek
CIO
15 Years of Experience
KL

Klára Langerová
Head of Investor Relations
Head of the Transfer Development Department at CETAV
invest@casinnovations.cz

MB

Michal Beluský
Head of lncubation
Head of the Transfer Project Department at CETAV